Gather the ingredients.
Heat oven to 350 F.
Combine 1/2 teaspoon each dried leaf basil, oregano, and marjoram, and a dash of dried rubbed sage for the Italian seasoning.
Combine the ground meats, about half of the tomato sauce, the bread crumbs, 1/2 cup of Parmesan cheese, eggs, garlic, onion, salt, black pepper, and Italian seasoning. Stir or mix until blended.
Pack into a lightly oiled loaf pan.
Bake for 1 hour and 10 minutes.
Carefully pour off the excess accumulated fat, and spread the remaining tomato sauce over the loaf; sprinkle with a few tablespoons of grated Parmesan cheese.
Continue baking for 10 to 15 minutes longer.
Turn out of the pan, slice, and serve.